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Overview:This case-based activity originally held as a satellite symposium in conjunction with MSVirtual2020 is designed to present several key analytic and diagnostic skills required to effectively characterize and treat neuromyelitis optica spectrum disorders (NMOSD). Presenting faculty work together through complex real-life cases that help to elucidate the major considerations and most common pitfalls in differentiating NMOSD from other neurodegenerative disorders such as multiple sclerosis.
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Program DescriptionMultiple Sclerosis impacts nearly 1 million people in the US and is the leading cause of non-traumatic disability in adults under the age of 50. Accordingly, substantial time and energy has been dedicated to improving understanding of its biological underpinnings and subsequent therapy development. As a result, there are now 18 different disease modifying therapies available representing nine therapeutic classes with several additional options poised to join them.
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Module 1: Diagnosis and Therapy InitiationThis module focuses on the timely and accurate diagnosis of MS through maximization of the latest technologies and strategies available. It will clarify the changes to the McDonald criteria and address the most common missteps in routine practice that currently pose risks to MS patients.
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This module will focus on key clinical factors and practical considerations that may impact DMT initiation as well as utilization of the diverse agents available. Factors discussed include age, radiologic versus clinical disease activity, and usefulness of distinguishing between MS categories. It will shed light on how well long-held theories have withstood the test of time and help to provide deeper insight into how experts are approaching the contemporary management of MS.
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This module will focus on topics of debate in the MS arena including best practices in DMT switching, the impact of race and pregnancy on DMT choice, and the potential role of neurofilament light (NfL) in routine practice.
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Program DescriptionIt has been well documented in the medical literature that despite the prevalence of migraine throughout the US population, several diagnostic and treatment gaps exist to this day. Despite these lingering performance gaps, insights into the pathophysiology of migraine and other related headache disorders have been advancing over the past decade or so, leading to 8 new medication approvals in just the past 2 years.
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Activity DescriptionNeuromyelitis optica spectrum disorder (NMOSD) is typically characterized by inflammation of the optic nerve and spinal cord but, more recently, has also been recognized to have cerebral or brainstem involvement. Given its clinical manifestation, NMOSD is frequently confused with other disorders such as multiple sclerosis or MOG-associated diseases and requires thorough understanding of diagnostic strategies to identify. In just the past 2 years, three agents specific to NMOSD have entered the armamentarium.
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Program DescriptionThe emergence of COVID-19 has created an unprecedented medical emergency that both raises new questions and presents updated information each day. This issue is even more pressing for patients with conditions such as multiple sclerosis (MS) who have altered immune systems from both chronic illness and disease modifying therapies (DMTs). While the advent of vaccines has revived hope for a return to normal life, vaccination is not always straightforward for those on or planning to start immunosuppressive therapies such as MS DMT. In this activity, Drs.
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OverviewThis activity, originally held as a satellite symposium in conjunction with the 2021 Consortium of Multiple Sclerosis (MS) Centers (CMSC) Annual Meeting, is designed to contextualize contemporary management approaches through the documented experiences of people with MS. Drs Benjamin Greenberg, Jennifer Graves, and Anthony Traboulsee present data from a large cohort of patients illustrating their perspectives on a variety of management issues related to their care.
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Program DescriptionEstimated to occur in up to a third of the general population with 25 or so different causes, excessive daytime sleepiness (EDS) can be difficult to trace back to its root cause. Some of the more prevalent disorders associated with this symptom include narcolepsy type 1 (NT-1), narcolepsy type 2 (NT-2), and idiopathic hypersomnia (IH). However, the lines between these disorders have been mobile and debated for years which has made their recognition and management challenging for treating clinicians.